KLHL23

Description		kelch like family member 23
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Common carotid intima-media thickness in HIV infection ( 29206233) Obesity-related traits ( 23251661) Platelet count ( 32888494) Plateletcrit ( 32888494)
Novel Interacting Genes		6 novel interacting genes: ANXA1 ANXA7 BBS5 BNIP3L CDKN1A TK1
Interacting Genes		6 interacting genes: ANXA1 ANXA7 BBS5 BNIP3L CDKN1A TK1
Entrez ID		151230
HPRD ID		11320
Ensembl ID		ENSG00000213160
Uniprot IDs		Q8NBE8
PDB IDs
Enriched GO Terms of Interacting Partners?		Epithelial Cell Differentiation Calcium-dependent Phospholipid Binding Keratinocyte Differentiation Phosphatidylserine Binding Vesicle Membrane Calcium-dependent Protein Binding Positive Regulation Of Programmed Cell Death Epidermal Cell Differentiation PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Thymidine Kinase Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of T-helper 2 Cell Differentiation Myoblast Migration Involved In Skeletal Muscle Regeneration Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Neutrophil Apoptotic Process Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Leukocyte Proliferation Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Cell-matrix Adhesion DNA Synthesis Involved In Mitotic DNA Replication Thymidine Biosynthetic Process Regulation Of Neutrophil Apoptotic Process Phospholipase A2 Inhibitor Activity Positive Regulation Of T-helper 1 Cell Differentiation Neutrophil Clearance Oncogene-induced Cell Senescence Stress-induced Premature Senescence Thymidine Metabolic Process BBSome
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