CRHR2

Description		corticotropin releasing hormone receptor 2
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GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Axon Terminus
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Corticotrophin-releasing Factor Receptor Activity Peptide Hormone Binding Corticotropin-releasing Hormone Receptor Activity
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Hormone-mediated Signaling Pathway Long-term Synaptic Potentiation Cellular Response To Corticotropin-releasing Hormone Stimulus
Pathways		G alpha (s) signalling events Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Type 2 diabetes ( 24509480 30297969)
Novel Interacting Genes		8 novel interacting genes: APP CRH GCC1 GPR35 MALL UCN UCN2 UCN3
Interacting Genes		8 interacting genes: APP CRH GCC1 GPR35 MALL UCN UCN2 UCN3
Entrez ID		1395
HPRD ID		03614
Ensembl ID		ENSG00000106113
Uniprot IDs		A0A090N7T4 Q13324
PDB IDs		3N93 3N95 3N96 6PB1 7TRY 7TS0
Enriched GO Terms of Interacting Partners?		Corticotropin-releasing Hormone Receptor 2 Binding Varicosity Positive Regulation Of CAMP/PKA Signal Transduction Hormone Activity Corticotropin-releasing Hormone Receptor Binding Regulation Of CAMP/PKA Signal Transduction Corticotropin-releasing Hormone Receptor 1 Binding Regulation Of Calcium Ion Transport Positive Regulation Of Corticotropin Secretion G Protein-coupled Receptor Binding Positive Regulation Of Behavioral Fear Response Regulation Of Corticotropin Secretion Positive Regulation Of Fear Response Associative Learning G Protein-coupled Receptor Signaling Pathway Regulation Of Metal Ion Transport Regulation Of Behavioral Fear Response Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Signaling Receptor Binding Regulation Of Monoatomic Ion Transport Response To Corticosterone Response To Glucocorticoid Response To Pain Perikaryon Hormone-mediated Signaling Pathway Positive Regulation Of Hormone Secretion Response To Auditory Stimulus Response To Corticosteroid Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Learning Response To Immobilization Stress Positive Regulation Of Calcium Ion Import Positive Regulation Of Behavior Digestion Neuropeptide Hormone Activity Regulation Of Peptide Hormone Secretion Response To Steroid Hormone Response To Mineralocorticoid Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Transport Regulation Of Hormone Secretion Regulation Of Calcium Ion Import Negative Regulation Of Blood Pressure Learning Or Memory Positive Regulation Of Secretion By Cell Regulation Of Transport Axon Terminus Cognition Positive Regulation Of Establishment Of Protein Localization
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