PWWP2A

Description		PWWP domain containing 2A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	Chromatin Binding Protein Binding Histone Binding NuRD Complex Binding Histone H3K36me3 Reader Activity
	Biological Process	Regulation Of Transcriptional Start Site Selection At RNA Polymerase II Promoter Chromatin Remodeling Positive Regulation Of Transcription Elongation By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: HAVCR2 PLEKHF2
Interacting Genes		2 interacting genes: HAVCR2 PLEKHF2
Entrez ID		114825
HPRD ID		19469
Ensembl ID		ENSG00000170234
Uniprot IDs		Q96N64
PDB IDs
Enriched GO Terms of Interacting Partners?		Early Endosome Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Negative Regulation Of Granulocyte Colony-stimulating Factor Production Negative Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Myeloid Dendritic Cell Activation Negative Regulation Of Interleukin-3 Production Negative Regulation Of Interferon-alpha Production Negative Regulation Of Immunological Synapse Formation Natural Killer Cell Tolerance Induction Negative Regulation Of Defense Response To Bacterium Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Regulation Of Tolerance Induction Dependent Upon Immune Response Toll-like Receptor 7 Signaling Pathway Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Natural Killer Cell Activation Negative Regulation Of T-helper 1 Type Immune Response Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Defense Response To Bacterium Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Immune Response To Tumor Cell Regulation Of Defense Response To Bacterium Tolerance Induction Regulation Of Tolerance Induction Macrophage Activation Involved In Immune Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Interleukin-4 Production Endolysosomal Toll-like Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Positive Regulation Of Macrophage Activation Regulation Of Response To Tumor Cell Maternal Process Involved In Female Pregnancy Regulation Of Interleukin-4 Production Mediator Complex Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type II Interferon Production Regulation Of Natural Killer Cell Activation Negative Regulation Of Type I Interferon Production Immunological Synapse Negative Regulation Of Interleukin-6 Production Regulation Of Natural Killer Cell Mediated Cytotoxicity Endosome To Lysosome Transport Regulation Of Macrophage Activation Regulation Of Natural Killer Cell Mediated Immunity Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Macrophage Activation Regulation Of Interleukin-2 Production Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Negative Regulation Of T Cell Proliferation
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