FICD

Description		FIC domain protein adenylyltransferase
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Transferase Activity Nucleotidyltransferase Activity Hydrolase Activity Hsp70 Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Adenylylhydrolase Activity Protein-folding Chaperone Binding AMPylase Activity
	Biological Process	Response To Unfolded Protein Protein Adenylylation Negative Regulation Of GTPase Activity Response To Endoplasmic Reticulum Stress Protein Deadenylylation Regulation Of IRE1-mediated Unfolded Protein Response
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Obesity-related traits ( 23251661) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Novel Interacting Genes		2 novel interacting genes: ADK HTT
Interacting Genes		2 interacting genes: ADK HTT
Entrez ID		11153
HPRD ID		13723
Ensembl ID		ENSG00000198855
Uniprot IDs		Q9BVA6
PDB IDs		4U04 4U07 4U0S 4U0U 4U0Z 6I7G 6I7H 6I7I 6I7J 6I7K 6I7L 6ZMD 7B7Z 7B80
Enriched GO Terms of Interacting Partners?		DATP Biosynthetic Process Adenosine Kinase Activity Deoxyadenosine Kinase Activity DAMP Salvage Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of CAMKK-AMPK Signaling Cascade GMP Salvage DATP Metabolic Process Regulation Of CAMKK-AMPK Signaling Cascade Positive Regulation Of Aggrephagy Positive Regulation Of Lipophagy Purine Ribonucleoside Salvage AMP Salvage Deoxyribonucleoside Triphosphate Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Vocal Learning Profilin Binding Observational Learning Nucleoside Salvage 2'-deoxyribonucleotide Biosynthetic Process Deoxyribonucleotide Biosynthetic Process GMP Biosynthetic Process AMP Biosynthetic Process Auditory Behavior Dynactin Binding Mechanosensory Behavior Purine Nucleobase Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Inclusion Body AMP Metabolic Process Positive Regulation Of Mitophagy Positive Regulation Of Cation Channel Activity Purine Nucleoside Metabolic Process Purine Nucleotide Salvage Positive Regulation Of Autophagy Of Mitochondrion GMP Metabolic Process Presynaptic Cytosol Postsynaptic Cytosol Purine-containing Compound Salvage Ribonucleoside Monophosphate Biosynthetic Process Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Ion Transmembrane Transporter Activity Dynein Intermediate Chain Binding Positive Regulation Of Cilium Assembly Synaptic Vesicle Transport Establishment Of Mitotic Spindle Orientation Nucleoside Monophosphate Biosynthetic Process Deoxyribonucleotide Metabolic Process Establishment Of Mitotic Spindle Localization
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