PRDM4

Description		PR/SET domain 4
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GO Annotations	Cellular Component	Nucleus Histone Methyltransferase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Metal Ion Binding Histone Methyltransferase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transcription By RNA Polymerase II Regulation Of Gene Expression Methylation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		p75NTR negatively regulates cell cycle via SC1
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Daytime nap ( 33568662) Sleep duration ( 30846698)
Novel Interacting Genes		13 novel interacting genes: CFTR CTNNBL1 DAO DYRK1A EIF4E EMX1 MSRB3 NCS1 RCAN1 RUNX1 SERTAD1 SMAD3 UNG
Interacting Genes		13 interacting genes: CFTR CTNNBL1 DAO DYRK1A EIF4E EMX1 MSRB3 NCS1 RCAN1 RUNX1 SERTAD1 SMAD3 UNG
Entrez ID		11108
HPRD ID		10425
Ensembl ID		ENSG00000110851
Uniprot IDs		B3KPI0 Q9UKN5
PDB IDs		2L9Z 3DB5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Extracellular Matrix Organization Transcription Coactivator Binding DNA-binding Transcription Factor Binding Transcription Corepressor Binding Enzyme Binding Response To Stress Positive Regulation Of Biomineral Tissue Development Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding D-serine Catabolic Process Glycine Oxidase Activity D-amino-acid Dehydrogenase Activity D-alanine Catabolic Process Histone H3T45 Kinase Activity Eukaryotic Initiation Factor 4G Binding Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Somatic Diversification Of Immunoglobulins
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