DSTN

Description		destrin, actin depolymerizing factor
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Exosome Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Actin Polymerization Or Depolymerization Actin Filament Depolymerization Actin Filament Fragmentation Positive Regulation Of Actin Filament Depolymerization Cell Motility Actin Filament Severing
Pathways
Drugs		Dodecyldimethylamine N-oxide
Diseases
GWAS		Coronary artery disease ( 29212778) Presence of antiphospholipid antibodies ( 23509613)
Novel Interacting Genes		10 novel interacting genes: ACTB ACTG1 CFTR FNDC3B SHBG SMAD9 SSH1 TAX1BP1 TESK2 VHL
Interacting Genes		10 interacting genes: ACTB ACTG1 CFTR FNDC3B SHBG SMAD9 SSH1 TAX1BP1 TESK2 VHL
Entrez ID		11034
HPRD ID		16446
Ensembl ID		ENSG00000125868
Uniprot IDs		P60981 V9HWA6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transepithelial Transport Dense Body Morphogenesis Of A Polarized Epithelium Structural Constituent Of Postsynaptic Actin Cytoskeleton Postsynaptic Cytoskeleton Organization Actin Filament-based Process Protein Localization To Cell-cell Junction Calyx Of Held Postsynaptic Actin Cytoskeleton Organization Actin Cytoskeleton Organization Anatomical Structure Morphogenesis Regulation Of Synaptic Vesicle Endocytosis NuA4 Histone Acetyltransferase Complex Apical Junction Complex Regulation Of Synaptic Vesicle Recycling Maintenance Of Blood-brain Barrier Platelet Aggregation Cell Junction Assembly Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Homotypic Cell-cell Adhesion Basal Body Patch Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Protein Localization To Cell Junction Actin Filament Regulation Of Norepinephrine Uptake Positive Regulation Of Anion Channel Activity Protein Localization To Phagocytic Vesicle Positive Regulation Of AMPA Glutamate Receptor Clustering Schaffer Collateral - CA1 Synapse Structural Constituent Of Cytoskeleton Cytoskeleton Organization Transporter Regulator Activity Positive Regulation Of Monoatomic Anion Transport Cell-cell Junction Assembly Cytoplasm Blood Microparticle Cell Junction Organization Multicellular Organismal-level Homeostasis Positive Regulation Of Enamel Mineralization Regulation Of AMPA Glutamate Receptor Clustering Regulation Of Postsynaptic Membrane Organization Regulation Of Cellular Localization Protein Localization To Adherens Junction Transepithelial Water Transport Androgen Binding Response To Purine-containing Compound Regulation Of Vesicle-mediated Transport
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