MAPRE2

Description		microtubule associated protein RP/EB family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cytoplasmic Microtubule Focal Adhesion Microtubule Cytoskeleton Microtubule Plus-end Spindle Midzone
	Molecular Function	Protein Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of ARF Protein Signal Transduction Protein Localization To Microtubule Spindle Assembly Cell Division Positive Regulation Of Keratinocyte Migration Positive Regulation Of Focal Adhesion Disassembly
Pathways
Drugs
Diseases
GWAS		Brugada syndrome ( 35210625) Cerebrospinal fluid AB1-42 levels ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial morphology ( 29921221) Metabolite levels ( 23823483)
Novel Interacting Genes		26 novel interacting genes: APC APP AURKA AURKB CASK CDK2 CDK4 CLASP2 CLIP1 DDIT4L FBXO7 GTSE1 KMT2E LMNA LMO2 LNX1 MAPRE3 NIF3L1 PAXIP1 RBM10 RBM6 SLAIN2 TRAF1 TRAIP TXN2 UBC
Interacting Genes		26 interacting genes: APC APP AURKA AURKB CASK CDK2 CDK4 CLASP2 CLIP1 DDIT4L FBXO7 GTSE1 KMT2E LMNA LMO2 LNX1 MAPRE3 NIF3L1 PAXIP1 RBM10 RBM6 SLAIN2 TRAF1 TRAIP TXN2 UBC
Entrez ID		10982
HPRD ID		16157
Ensembl ID		ENSG00000166974
Uniprot IDs		Q15555
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Microtubule Polymerization Or Depolymerization Microtubule Plus-end Binding Regulation Of Microtubule-based Process Regulation Of Microtubule Cytoskeleton Organization Microtubule Cytoskeleton Microtubule-based Process Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Supramolecular Fiber Organization Cytoplasmic Microtubule Regulation Of Microtubule Polymerization Centrosome Microtubule Cytoskeleton Organization Kinetochore Cell Cycle Phase Transition Microtubule Plus-end Spindle Midzone Regulation Of Cell Cycle Process Microtubule Spindle Assembly Regulation Of Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Microtubule Depolymerization Positive Regulation Of Cellular Component Organization Cytoskeleton Chromosome Passenger Complex Spindle Microtubule Microtubule Binding Regulation Of Organelle Organization Positive Regulation Of Mitotic Cell Cycle Cell Division Membraneless Organelle Assembly Mitotic Cell Cycle Phase Transition Ubiquitin Protein Ligase Binding Cell Cycle G2/M Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Spindle Organization Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cytoskeleton Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Negative Regulation Of Cell Cycle G1/S Phase Transition Identical Protein Binding Regulation Of Cell Cycle G1/S Phase Transition Protein Serine Kinase Activity Nuclear Lamina
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