THOC1 and IK

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid)

		THOC1	IK
Description		THO complex 1	IK cytokine
Image
GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Mitotic Spindle Pole
	Molecular Function	DNA Binding RNA Binding Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of DNA Recombination RNA Processing MRNA Processing MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint	Mitotic Cell Cycle MRNA Splicing, Via Spliceosome Mitotic Spindle Assembly Checkpoint Signaling Protein Localization To Kinetochore
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799) Triglyceride levels ( 32203549)	Monocyte count ( 32888494) Schizophrenia ( 29483656) Serum immune biomarker levels ( 32066700)
Interacting Genes		28 interacting genes: AGR2 AKAP9 ATP1B1 BHLHB9 CTAG1A CTAG1B DHX8 EXOC5 FRA10AC1 IK MAGEB4 MOAP1 MTNR1B NEDD4 PAX6 PPP1R12C RABGEF1 RB1 REL SAP30BP SF3B2 TADA2A TRIM27 TRIM54 TYMS USHBP1 WDR77 ZMYND12	27 interacting genes: APP CEP70 CHD3 CTNNBL1 DDX6 EGLN3 FANCC FRA10AC1 FXR1 GRB2 KAT5 KDM1A MBD3 MFAP1 NUP62 OGT PFN2 QARS1 RACK1 RBM10 SUPT5H THOC1 TOE1 TRIM55 TRIM63 TTC14 ZCCHC10
Entrez ID		9984	3550
HPRD ID		09498	02771
Ensembl ID		ENSG00000079134	ENSG00000113141
Uniprot IDs		Q96FV9	Q13123 Q95HA6 Q9UK43
PDB IDs		1WXP 7APK	5O9Z 6Q8I
Enriched GO Terms of Interacting Partners?
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