MED12 and MED13

Number of citations of the paper that reports this interaction (PubMedID 15175163)
129

Data Source:
HPRD (in vivo, in vitro)

		MED12	MED13
Description		mediator complex subunit 12	mediator complex subunit 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Membrane Mediator Complex	Nucleus Nucleoplasm Membrane Mediator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Protein Domain Specific Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Ubiquitin Protein Ligase Activity	Transcription Coregulator Activity Transcription Coactivator Activity Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Endoderm Development Heart Development Oligodendrocyte Development Schwann Cell Development Protein Ubiquitination Stem Cell Population Maintenance Spinal Cord Development Post-anal Tail Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Axis Elongation Involved In Somitogenesis Embryonic Brain Development	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Uterine fibroids ( 31649266)	Coffee consumption ( 31046077) Initial pursuit acceleration ( 29064472) Objective response to lithium treatment ( 26503763) PR segment duration ( 24850809)
Interacting Genes		18 interacting genes: CDK8 ESR1 ESR2 GLI3 LYST MED1 MED13 MED26 MED29 MED8 MED9 NANOG PPARGC1A SGCE SOX9 SREBF1 TAF1 VDR	9 interacting genes: ENO1 ESR1 MED12 MED13L MED23 MED29 MED9 SREBF1 TSC22D2
Entrez ID		9968	9969
HPRD ID		02176	07229
Ensembl ID		ENSG00000184634	ENSG00000108510
Uniprot IDs		Q93074	A0A024QZ75 Q9UHV7
PDB IDs
Enriched GO Terms of Interacting Partners?
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