SETDB1 and CDK4

  • Number of citations of the paper that reports this interaction (PubMedID 16169070)
  • 888
  • Data Source:
  • BioGRID (two hybrid, two hybrid)
  • HPRD (two hybrid)

SETDB1

CDK4

Description SET domain bifurcated histone lysine methyltransferase 1 cyclin dependent kinase 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
  • Caffeine consumption from coffee or tea ( 33287642)
  • Caffeine consumption from tea ( 33287642)
  • Chronic kidney disease ( 20383146)
  • Coffee consumption ( 31046077)
  • Cutaneous squamous cell carcinoma ( 32041948)
  • Hip circumference adjusted for BMI ( 34021172)
  • Melanoma ( 21983785)
  • Neurological blood protein biomarker levels ( 31320639)
  • Nevus count or cutaneous melanoma ( 30429480)
Interacting Genes 110 interacting genes: AIFM1 AKT1 ANXA7 APC APLP1 ASAH1 ATF7IP ATF7IP2 BAG6 BARD1 BHLHE40 BID BRIX1 BTBD2 C11orf1 CBX8 CCDC106 CDK4 CDKN1A CLSTN1 CREBBP CRELD1 DAP DLEU1 DNMT3A ECSIT ERG ERH FAM118B FLYWCH1 GIPC2 GPS2 GRB7 GSTO1 H3-4 H3C1 H3C15 H4-16 HDAC1 HDAC2 HMOX2 HSF2BP HSPB3 JARID2 KDM1A LRIF1 LUC7L2 MAD2L1BP MAP4K5 MBD1 MDM2 MOB4 MRPL44 MZT2B NIPSNAP3A OLFML3 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PGAM5 PHF10 PIAS4 PLEKHA4 POLA2 PPA1 PPP1R8 PRKRA PSMD11 PSME1 PTPRS QTRT1 RIF1 RNF10 S100A10 SAT1 SERPINB9 SIN3A SIN3B SKIL SLC38A3 SMN1 SNIP1 SUFU SULT1E1 SUMO2 TARDBP TCERG1 THAP8 TK1 TOB1 TOLLIP TPI1 TRBV2 TRDMT1 TRIB3 TRIM16 TRIM28 TRIP6 TSC22D1 TSPAN15 TTR TXNDC9 UBE2I ULK2 USP11 VIM ZFP64 ZNF24 148 interacting genes: AGAP2 AKT1 ANKRD12 ANXA7 APLP1 APP ARAF ARID4A ARNT ATP5F1B BAG6 BCL11A BECN1 BIRC5 BMPR1B BRCA1 CA10 CAMK1 CAPN1 CAPNS1 CCND1 CCND2 CCND3 CCNE1 CD44 CDC37 CDC45 CDC6 CDC7 CDK6 CDKN1A CDKN1B CDKN1C CDKN2A CDKN2B CDKN2C CDKN2D CEBPA CIB1 CNOT7 CNTN2 CTDSP2 DAZAP2 DDAH2 DUSP9 EIF4EBP2 EPHA2 ERBB2 FBXO8 FGFR4 FOXM1 FZR1 GLIS2 GNS GRM1 H1-0 H1-1 H1-3 HGF HIF1A HMGXB3 HOOK1 HSP90AA1 IFI27 IFNG IGF1R IKZF3 IL15RA INCA1 IRF7 KDELR2 LATS2 LNX2 LUC7L2 LY75 MAP2K3 MAP2K5 MAP3K5 MAPK14 MAPRE2 MARCKS MCM2 MDM4 MET MYC MYOD1 MZF1 NCOA2 NF2 NOL12 OGDHL OPTN ORC3 OTX2 PDGFRA PGD PIAS1 PKM POLD1 PPP2R1B PRKAR1A PSMD10 PTMA QARS1 RAF1 RAP2A RASSF1 RB1 RBL1 RBL2 RFC1 RFC4 RNF139 RPL34 SENP3 SERTAD1 SETDB1 SHOX2 SKP1 SLBP SMAD2 SMAD3 SNCA SPOP STK11 STUB1 TEAD2 TERT TGFBR1 TK1 TP53 TRMT2A TSC1 TSPYL2 UBE3A UBTF UHRF2 USP15 USP17L2 USP51 VTA1 WDR33 YBX3 ZBTB16 ZNF101 ZNF219 ZNF335 ZNF655
Entrez ID 9869 1019
HPRD ID 06828 00447
Ensembl ID ENSG00000143379 ENSG00000135446
Uniprot IDs Q15047 A0A024RBB6 P11802
PDB IDs 3DLM 4X3S 5KCH 5KCO 5KE2 5KE3 5KH6 5QT1 5QT2 6AU2 6AU3 6BHD 6BHE 6BHG 6BHH 6BHI 6BPI 1LD2 2W96 2W99 2W9F 2W9Z 3G33 5FWK 5FWL 5FWM 5FWP 6P8E 6P8F 6P8G 6P8H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?