RB1CC1 and ITIH5

Number of citations of the paper that reports this interaction (PubMedID 25640309)
8

Data Source:
BioGRID (two hybrid)

		RB1CC1	ITIH5
Description		RB1 inducible coiled-coil 1	inter-alpha-trypsin inhibitor heavy chain 5
Image			No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Lysosome Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Extracellular Region Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding Protein Kinase Binding Molecular Adaptor Activity	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Liver Development Positive Regulation Of Protein Phosphorylation Autophagy Cell Cycle Heart Development Autophagy Of Peroxisome Piecemeal Microautophagy Of The Nucleus Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Reticulophagy Glycophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)	Blood protein levels ( 30072576 29875488) Brain morphology (MOSTest) ( 32665545) Leftâ€“right brain asymmetry ( 33723403) Metabolite levels ( 23823483) Planum temporale asymmetry index ( 31887566)
Interacting Genes		33 interacting genes: AZI2 BAP1 BLID COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 TAX1BP1 TBKBP1 THRSP UBC UMPS VHL VPS45 WIF1	10 interacting genes: BAG4 BRCA1 CHEK2 ESR2 HMMR NOTCH2 PPM1D RAD51 RB1CC1 XRCC3
Entrez ID		9821	80760
HPRD ID		06019	13747
Ensembl ID		ENSG00000023287	ENSG00000123243
Uniprot IDs		Q8TDY2	A0A096LP62 C9J2H1 G5E9D8 Q86UX2 Q96JW9
PDB IDs		6DCE 6GMA
Enriched GO Terms of Interacting Partners?
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