SPCS2 and STMN3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		SPCS2	STMN3
Description		signal peptidase complex subunit 2	stathmin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Cytoplasm Golgi Apparatus Cytosol Growth Cone Neuron Projection
	Molecular Function	Peptidase Activity	Protein Binding Tubulin Binding Protein Domain Specific Binding
	Biological Process	Signal Peptide Processing Protein Targeting To ER	Blastocyst Hatching Microtubule Depolymerization Nervous System Development Regulation Of Microtubule Polymerization Or Depolymerization Cytoplasmic Microtubule Organization Neuron Projection Development Negative Regulation Of Rac Protein Signal Transduction Regulation Of GTPase Activity Regulation Of Cytoskeleton Organization
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Mean corpuscular hemoglobin ( 32888494) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		5 interacting genes: ATP13A2 CLN8 EGFR STMN3 TEFM	27 interacting genes: ANKRD11 C1orf109 CARD9 CLIC3 EXOC8 GLP1R GPANK1 HGS KAT5 KIFC3 KRT34 LTB4R2 MIPOL1 MKRN3 MNS1 NKX3-1 P4HA3 PLEKHA7 POLR1C SMARCD1 SPCS2 TBC1D21 TRIM69 TRPC5 TXLNB UBQLN1 ZNF76
Entrez ID		9789	50861
HPRD ID		15435	16324
Ensembl ID		ENSG00000118363	ENSG00000197457
Uniprot IDs		Q15005	Q9NZ72
PDB IDs
Enriched GO Terms of Interacting Partners?
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