PHACTR2 and G3BP2

		PHACTR2	G3BP2
Description		phosphatase and actin regulator 2	G3BP stress granule assembly factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Platelet Alpha Granule Membrane	Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding	RNA Binding MRNA Binding Protein Binding Signaling Receptor Complex Adaptor Activity
	Biological Process	Actin Cytoskeleton Organization Negative Regulation Of Catalytic Activity	Cytoplasmic Sequestering Of NF-kappaB Ras Protein Signal Transduction Stress Granule Assembly Innate Immune Response MRNA Transport Protein Homooligomerization Positive Regulation Of Stress Granule Assembly
Pathways		Platelet degranulation
Drugs
Diseases
GWAS		3-month functional outcome in non-lacunar ischaemic stroke (modified Rankin score) ( 30796134) Erectile dysfunction in type 1 diabetes ( 22704111) Inflammatory bowel disease ( 23128233) Lung Cancer (DNA repair capacity) ( 23108145) Obesity-related traits ( 23251661) Perceived sweetness of sucrose ( 31005972)	HDL cholesterol levels ( 32203549) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763) Testicular germ cell tumor ( 28604728)
Interacting Genes		1 interacting genes: G3BP2	66 interacting genes: AGO4 CDKL2 DANCR MDM2 MIR1-1 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR19A MIR19B1 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR363 MIR429 MIR7-1 MIR7-2 MIR7-3 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKB1 NFKBIA OGT PHACTR2 PIN1 SDAD1 USO1 ZNF618
Entrez ID		9749	9908
HPRD ID		16378	06570
Ensembl ID		ENSG00000112419	ENSG00000138757
Uniprot IDs		O75167	A0A024RDB2 A0A024RDE5 Q9UN86
PDB IDs			5DRV
Enriched GO Terms of Interacting Partners?
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