PPM1F and FEM1B

Number of citations of the paper that reports this interaction (PubMedID 11559703)
18

Data Source:
BioGRID (affinity chromatography technology, pull down)

		PPM1F	FEM1B
Description		protein phosphatase, Mg2+/Mn2+ dependent 1F	fem-1 homolog B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Death Receptor Binding Protein Binding Ubiquitin Ligase-substrate Adaptor Activity
	Biological Process	Negative Regulation Of Protein Kinase Activity Protein Dephosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Histone Dephosphorylation Positive Regulation Of Cell Migration Negative Regulation Of Peptidyl-serine Phosphorylation Peptidyl-threonine Dephosphorylation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Growth Positive Regulation Of Chemotaxis Negative Regulation Of Protein Transport Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Peptidyl-serine Dephosphorylation Cellular Response To Xenobiotic Stimulus Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Localization Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin	Apoptotic Process Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Branching Involved In Prostate Gland Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of DNA Damage Checkpoint
Pathways		Negative regulation of NMDA receptor-mediated neuronal transmission	Neddylation
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 18839057) Bipolar disorder ( 31043756)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Major depressive disorder ( 23377640) Systolic blood pressure ( 26969751)
Interacting Genes		20 interacting genes: AATK ARHGEF7 CAMK2A ERBB2 ERBB3 ERBB4 FAM161A FEM1A FEM1B KLHL8 LATS1 LMTK2 MARS1 MEOX1 OGT PAK1 PRKAA1 PTK7 ROR1 ROR2	8 interacting genes: APAF1 FAS GLI1 KIAA0319 NKX3-1 PPM1F RAD9A TLE3
Entrez ID		9647	10116
HPRD ID		10163	16889
Ensembl ID		ENSG00000100034	ENSG00000169018
Uniprot IDs		B5MCT7 P49593	Q9UK73
PDB IDs			6LBF 7CNG
Enriched GO Terms of Interacting Partners?
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