TCL1B and PLEKHA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		TCL1B	PLEKHA3
Description		TCL1 family AKT coactivator B	pleckstrin homology domain containing A3
Image		No pdb structure
GO Annotations	Cellular Component	Protein-containing Complex	Golgi Membrane Golgi Apparatus Cytosol Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity	Protein Binding Identical Protein Binding Phosphatidylinositol-4-phosphate Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity	Biological_process Ceramide Transport Intermembrane Lipid Transfer Ceramide 1-phosphate Transport
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		17 interacting genes: AKT1 AKT2 APP BAG4 EFCAB2 GLRX3 LSM1 LSM5 LSM7 MARK1 MEIS3 MKRN3 PLEKHA3 PNMA1 SNRPG TNPO2 ZNF330	9 interacting genes: DOK3 ERRFI1 MORF4L1 MRPL45 MYO15B PRKRA RNMT SH2B2 TCL1B
Entrez ID		9623	65977
HPRD ID		04795	09688
Ensembl ID		ENSG00000213231	ENSG00000116095
Uniprot IDs		A0A024R6P4 O95988	Q9HB20
PDB IDs			2KCJ 2MDX 3RCP
Enriched GO Terms of Interacting Partners?
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