RNF7 and UBE2Q1

Number of citations of the paper that reports this interaction (PubMedID 19549727)
74

Data Source:
BioGRID (two hybrid)

		RNF7	UBE2Q1
Description		ring finger protein 7	ubiquitin conjugating enzyme E2 Q1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex	Nucleus Cytosol Filopodium
	Molecular Function	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Protein Neddylation Response To Redox State	Protein Polyubiquitination Suckling Behavior Embryo Implantation Mating Behavior Fertilization Reproductive System Development Prolactin Secretion
Pathways		Neddylation Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)	Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
Interacting Genes		41 interacting genes: APOBEC3F APOBEC3G ASB11 BTRC CASP7 CBFB CDC34 CHFR CREBBP CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2L3 UBE2M UBE2Q1	13 interacting genes: ECPAS FHL3 IRF2BPL ITCH LMNA MDM2 OGT RNF26 RNF31 RNF7 STUB1 TP53 UBC
Entrez ID		9616	55585
HPRD ID		04840	15601
Ensembl ID		ENSG00000114125	ENSG00000160714
Uniprot IDs		Q9UBF6	Q7Z7E8
PDB IDs		2ECL	2QGX
Enriched GO Terms of Interacting Partners?
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