CDC42BPB and KLC1

		CDC42BPB	KLC1
Description		CDC42 binding protein kinase beta	kinesin light chain 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Lamellipodium Cell Leading Edge Actomyosin Extracellular Exosome	Cytosol Kinesin Complex Microtubule Membrane Growth Cone Cytoplasmic Vesicle
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Small GTPase Binding Protein-containing Complex Binding Protein Serine Kinase Activity	Cytoskeletal Motor Activity Protein Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Migration Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction	Stress Granule Disassembly
Pathways		CDC42 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Signaling by ALK fusions and activated point mutants Kinesins
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body shape index ( 34021172) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494) Refractive error ( 32231278) Serum alkaline phosphatase levels ( 33547301) Waist circumference adjusted for body mass index ( 34021172)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 25056061) Smoking behaviour (cigarette pack-years) ( 30679032) Urate levels ( 31578528)
Interacting Genes		10 interacting genes: AMN CDC42 CDC42BPA KLC1 MAP2K5 MARK3 PPM1A PPP2CA PYGM RIPK1	33 interacting genes: ADRB2 AP1AR APP ATCAY BNIP2 CDC42BPB CLSTN1 ERBB2 F2RL1 GPR132 HSPB1 JAG2 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 NIN ODAD1 ODF1 PCM1 PLEKHM2 POLR1E PTGER4 SNCA SPAG9 TACC3 TSC1 YWHAB
Entrez ID		9578	3831
HPRD ID		08516	02489
Ensembl ID		ENSG00000198752	ENSG00000126214
Uniprot IDs		A0A024R6N2 Q86XZ8 Q9Y5S2	Q07866 Q7RTQ2
PDB IDs		3QFV 3TKU 4UAK 4UAL 5OTE 5OTF	3NF1 5OJ8
Enriched GO Terms of Interacting Partners?
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