ATP5MF and NECTIN2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5MF	NECTIN2
Description		ATP synthase membrane subunit f	nectin cell adhesion molecule 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Integral Component Of Membrane Nuclear Membrane	Plasma Membrane Cell-cell Junction Zonula Adherens Focal Adhesion Cell Surface Integral Component Of Membrane Apical Junction Complex Cell-cell Contact Zone Extracellular Exosome
	Molecular Function	Proton-transporting ATP Synthase Activity, Rotational Mechanism	Virus Receptor Activity Protein Binding Coreceptor Activity Identical Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Mitochondrial ATP Synthesis Coupled Proton Transport Proton Transmembrane Transport	Acrosome Assembly Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immunoglobulin Mediated Immune Response Cytoskeleton Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Spermatid Development Spermatid Nucleus Differentiation Fertilization Fusion Of Virus Membrane With Host Plasma Membrane Sperm Mitochondrion Organization Cell Part Morphogenesis Positive Regulation Of Mast Cell Activation Susceptibility To Natural Killer Cell Mediated Cytotoxicity Adhesion Of Symbiont To Host Cilium Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Viral Entry Into Host Cell Coreceptor-mediated Virion Attachment To Host Cell Positive Regulation Of T Cell Receptor Signaling Pathway Establishment Of Mitochondrion Localization Susceptibility To T Cell Mediated Cytotoxicity
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases
GWAS			Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 30498476) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Urate levels ( 31578528)
Interacting Genes		14 interacting genes: ARL8B CAPNS1 CCDC137 CDC42 CRELD1 FBP1 HAP1 KDM1A LPP NDUFA6 NECTIN2 PRPF4 RPLP1 ZFPL1	37 interacting genes: AFDN ATP5MF CD226 CYSRT1 DUS2 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP5-9 LCE1C LCE2B LCE2C LCE5A LYRM4 MAPK6 MDFI MEOX2 NBPF19 NECTIN3 NECTIN4 NOTCH2NLA NR4A3 P4HB PICK1 PVR RGS20 SIAH1 TCF4 TGM1 TIGIT USP53
Entrez ID		9551	5819
HPRD ID		16520	02879
Ensembl ID		ENSG00000241468	ENSG00000130202
Uniprot IDs		P56134	Q92692
PDB IDs			3R0N 4DFH 4DFI 4HZA 5V52
Enriched GO Terms of Interacting Partners?
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