TP53I3 and RAB10

		TP53I3	RAB10
Description		tumor protein p53 inducible protein 3	RAB10, member RAS oncogene family
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GO Annotations	Cellular Component	Cytosol	Golgi Membrane Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Synaptic Vesicle Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network
	Molecular Function	NADPH:quinone Reductase Activity Protein Homodimerization Activity Quinone Binding NADPH Binding	G Protein Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	NADP Metabolic Process	Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Axonogenesis Protein Secretion Vesicle-mediated Transport Endosomal Transport Regulation Of Exocytosis Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Glycated hemoglobin levels ( 34059833) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000) Platelet distribution width ( 32888494)
Interacting Genes		7 interacting genes: EEF1G FUNDC2 GPX3 MDM2 RAB10 UBR1 UNC119	17 interacting genes: APP ATRAID DNAJC27 EFR3B ENOPH1 EVI5L GPN1 IFT172 MICAL1 MTNR1A PLP2 PPBP PREB RABIF RIMS1 SEPTIN9 TP53I3
Entrez ID		9540	10890
HPRD ID		05527	06692
Ensembl ID		ENSG00000115129	ENSG00000084733
Uniprot IDs		B4DMQ7 Q53FA7	P61026
PDB IDs		2J8Z 2OBY	5LPN 5SZJ
Enriched GO Terms of Interacting Partners?
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