TBPL1 and LSM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TBPL1	LSM5
Description		TATA-box binding protein like 1	LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIA Complex Cytoplasm	Nucleus Nucleoplasm U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity General Transcription Initiation Factor Activity	RNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Acrosome Assembly DTTP Biosynthetic Process DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Spermatid Nucleus Differentiation	MRNA Splicing, Via Spliceosome MRNA Processing MRNA Catabolic Process Response To Bacterium
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 28552196) Night sleep phenotypes ( 27126917)	Body mass index ( 26426971) Extremely high intelligence ( 29520040) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Morning person ( 30696823) Palmitic acid (16:0) levels ( 23362303) Smooth-surface caries ( 24556642)
Interacting Genes		18 interacting genes: ABCF3 APP DVL3 FBXO7 GTF2A1 GTF2A2 GTF2B IRAK4 LSM5 NDUFA6 NF1 PLIN3 PRNP PTCD3 RAB35 RPL10 SLC35F6 TNNT1	16 interacting genes: DDIT4L EXOSC5 HNRNPD LSM1 LSM2 LSM3 LSM6 LSM7 LSM8 PLK3 SMN1 SNRPE SNRPF TBPL1 TCL1B TEX43
Entrez ID		9519	23658
HPRD ID		09272	06285
Ensembl ID		ENSG00000028839	ENSG00000106355
Uniprot IDs		P62380	A0A090N8Y5 Q9Y4Y9
PDB IDs			3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG
Enriched GO Terms of Interacting Partners?
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