MED20 and POLR1B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		MED20	POLR1B
Description		mediator complex subunit 20	RNA polymerase I subunit B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mediator Complex	Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Cytosol
	Molecular Function	Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ribonucleoside Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated	Embryo Implantation RRNA Transcription Neural Crest Formation Nucleologenesis
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Mean corpuscular hemoglobin ( 20139978 27863252) Mean corpuscular volume ( 23263863 20139978 27863252) Metabolite levels ( 23823483) Red blood cell count ( 20139978)
Interacting Genes		16 interacting genes: ANKS1A CD300C CYB5R2 ERP27 ESR1 ESR2 GABPB1 MARK4 MED18 MED29 MED8 PIH1D2 POLR1B PSORS1C2 TRIM69 YY1	14 interacting genes: AKT2 CCND1 EIF3L ESR1 GIT2 HDAC6 LDB1 LZTR1 MED20 NFKBIB POLR1E RPL37 RRN3 ZNF207
Entrez ID		9477	84172
HPRD ID		15638	06852
Ensembl ID		ENSG00000124641	ENSG00000125630
Uniprot IDs		B3KUJ9 Q9H944	B7Z1W6 Q9H9Y6
PDB IDs
Enriched GO Terms of Interacting Partners?
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