EIF4E2 and TADA2A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		EIF4E2	TADA2A
Description		eukaryotic translation initiation factor 4E family member 2	transcriptional adaptor 2A
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GO Annotations	Cellular Component	P-body Cytoplasm Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex	SAGA Complex Nucleus Chromosome SAGA-type Complex
	Molecular Function	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding
	Biological Process	Translational Initiation Negative Regulation Of Translation Gene Silencing By RNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways		ISG15 antiviral mechanism	HATs acetylate histones
Drugs
Diseases
GWAS		Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520) Refractive error ( 32231278)	Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Monocyte percentage of white cells ( 32888494) Ovarian cancer ( 23535730) Plateletcrit ( 32888494) White blood cell count ( 32888494)
Interacting Genes		51 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CAB39 CARD9 CBY2 CCL24 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MGAT5B MIPOL1 MVK MYOG NECAB2 NOTCH2NLA PDE4DIP PRDM14 REL SAG SP140 SPAG5 SPRY2 TADA2A TCF4 TGFBRAP1 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9	49 interacting genes: ARNT2 C1orf109 CCDC116 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 LMO1 MAGOH MAGOHB MCPH1 MFAP1 MKRN3 MTX2 MYC NFE2L2 NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 QARS1 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 THOC1 TTC23 TTC9C VPS25 ZCCHC12 ZFYVE26 ZNF417 ZNF564 ZNF688
Entrez ID		9470	6871
HPRD ID		05798	03784
Ensembl ID		ENSG00000135930	ENSG00000276234
Uniprot IDs		B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1	A0A024R0Y4 A0A087WWR4 B3KU13 O75478
PDB IDs		2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN	1X41
Enriched GO Terms of Interacting Partners?
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