CAMK2N2 and ARHGAP32

Number of citations of the paper that reports this interaction (PubMedID 12531901)
53

Data Source:
HPRD (in vitro)

		CAMK2N2	ARHGAP32
Description		calcium/calmodulin dependent protein kinase II inhibitor 2	Rho GTPase activating protein 32
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol	Golgi Membrane Fibrillar Center Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cell Cortex Endosome Membrane Postsynaptic Density Actin Cytoskeleton Dendritic Spine
	Molecular Function	Calcium-dependent Protein Kinase Inhibitor Activity Protein Kinase Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity	Small GTPase Mediated Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)	Intracranial aneurysm ( 30823506) Iris color (L* coordinate) ( 29109912) Macular thickness ( 30535121) Metabolite levels (5-HIAA) ( 23319000) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: ARHGAP32 CAMK2A CAMK2B LNX1	33 interacting genes: ABI2 ATXN1 BCAR1 CAMK2N2 CDC42 CDH1 CDH2 CRK CRKL CTNNB1 DLG4 DZIP3 FYN GAB1 GAB2 GRAP GRB2 GRIN2A GRIN2B LHX2 MDFI MEGF10 NCK1 NCK2 NPHP1 NTRK1 PIK3R1 PLCG1 RAC1 RHOA SHC3 SRC TLE5
Entrez ID		94032	9743
HPRD ID		16377	12257
Ensembl ID		ENSG00000163888	ENSG00000134909
Uniprot IDs		Q96S95	A7KAX9 Q86T64
PDB IDs			3IUG
Enriched GO Terms of Interacting Partners?
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