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SLC9A3R1 and BCL10
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
87
Data Source:
BioGRID
(two hybrid)
SLC9A3R1
BCL10
Description
SLC9A3 regulator 1
BCL10 immune signaling adaptor
Image
GO Annotations
Cellular Component
Ruffle
Nucleus
Cytoplasm
Microvillus
Endomembrane System
Actin Cytoskeleton
Membrane
Apical Plasma Membrane
Filopodium
Brush Border Membrane
Microvillus Membrane
Vesicle
Stereocilium Tip
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cell Periphery
Sperm Midpiece
Plasma Membrane Protein Complex
Immunological Synapse
Polkadots
Nucleus
Cytoplasm
Lysosome
Cytosol
Cytoplasmic Microtubule
CBM Complex
Protein-containing Complex
Membrane Raft
Perinuclear Region Of Cytoplasm
Molecular Function
Signaling Receptor Binding
Protein Binding
Beta-catenin Binding
Gamma-aminobutyric Acid Transmembrane Transporter Activity
Chloride Channel Regulator Activity
Phosphatase Binding
PDZ Domain Binding
Beta-2 Adrenergic Receptor Binding
Type 2 Metabotropic Glutamate Receptor Binding
Type 3 Metabotropic Glutamate Receptor Binding
Protein-membrane Adaptor Activity
Protein Self-association
Protein-containing Complex Binding
Myosin II Binding
Protein N-terminus Binding
Dopamine Receptor Binding
Growth Factor Receptor Binding
Protease Binding
Transcription Coactivator Activity
Protein Binding
Protein C-terminus Binding
Kinase Activator Activity
Enzyme Binding
Kinase Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Protein Kinase B Binding
Protein Self-association
Protein-containing Complex Binding
CARD Domain Binding
NF-kappaB Binding
General Transcription Initiation Factor Binding
Biological Process
Morphogenesis Of An Epithelium
Renal Sodium Ion Transport
Plasma Membrane Organization
Nuclear Migration
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Sensory Perception Of Sound
Negative Regulation Of Cell Population Proliferation
Regulation Of Cell Shape
Regulation Of Cell Size
Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Wnt Signaling Pathway
CAMP-mediated Signaling
Gland Morphogenesis
Microvillus Assembly
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Cellular Phosphate Ion Homeostasis
Regulation Of Sodium:proton Antiporter Activity
Negative Regulation Of Sodium:proton Antiporter Activity
Bile Acid Secretion
Glutathione Transport
Positive Regulation Of Ion Transmembrane Transport
Regulation Of Excretion
Cilium Organization
Establishment Of Epithelial Cell Apical/basal Polarity
Maintenance Of Epithelial Cell Apical/basal Polarity
Regulation Of Protein Kinase Activity
Negative Regulation Of Mitotic Cell Cycle
Establishment Of Golgi Localization
Negative Regulation Of Protein Kinase B Signaling
Gamma-aminobutyric Acid Import
Auditory Receptor Cell Stereocilium Organization
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Protein-containing Complex Assembly
Renal Absorption
Negative Regulation Of ERK1 And ERK2 Cascade
Protein Localization To Plasma Membrane
Negative Regulation Of Canonical Wnt Signaling Pathway
Cerebrospinal Fluid Circulation
Renal Phosphate Ion Absorption
Import Across Plasma Membrane
Transport Across Blood-brain Barrier
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
B Cell Apoptotic Process
Neural Tube Closure
Toll-like Receptor Signaling Pathway
Adaptive Immune Response
Negative Regulation Of Mature B Cell Apoptotic Process
Cellular Defense Response
I-kappaB Kinase/NF-kappaB Signaling
Cell Death
Immunoglobulin Mediated Immune Response
Positive Regulation Of Protein Ubiquitination
Lipopolysaccharide-mediated Signaling Pathway
Response To Food
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Lymphotoxin A Production
Positive Regulation Of Mast Cell Cytokine Production
Positive Regulation Of Kinase Activity
Positive Regulation Of Phosphorylation
Positive Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Activation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Homooligomerization
Antifungal Innate Immune Response
T Cell Apoptotic Process
Cellular Response To Lipopolysaccharide
Cellular Response To Mechanical Stimulus
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Activation of NF-kappaB in B cells
Activation of NF-kappaB in B cells
Downstream TCR signaling
FCERI mediated NF-kB activation
FCERI mediated NF-kB activation
CLEC7A (Dectin-1) signaling
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Dental caries (decayed and filled deciduous teeth) (
31533690
)
Dental caries (decayed and filled deciduous tooth surfaces) (
31533690
)
Fibrinogen (
20031577
)
Lymphocyte counts (
32888494
)
Monocyte count (
27863252
)
Monocyte percentage of white cells (
32888494
27863252
)
Neutrophil count (
32888494
)
White blood cell count (
32888494
)
Metabolite levels (
23823483
)
Multiple sclerosis (
24076602
)
Interacting Genes
70 interacting genes:
ABCC2
ABCC4
ACE2
ADRB2
AKAP10
AKT1
APPBP2
ATP6V1B1
ATP6V1E1
AXIN2
BCL10
BCL2A1
CABP1
CD300A
CFTR
CLCN3
CNGA2
COG1
CRABP1
CTNNB1
DLGAP4
EGFR
EZR
GC
GFI1
GNA11
GNAQ
GRK6
KCNJ1
LHCGR
LPAR2
MSN
NF2
NOS2
OGT
OPRK1
P2RY1
PAG1
PDGFRA
PDGFRB
PDZK1
PHLPP1
PLCB1
PLCB2
PRKCA
PTEN
PTH1R
RDX
RLBP1
SCN4A
SKP2
SLC13A1
SLC22A11
SLC22A4
SLC22A5
SLC22A9
SLC26A3
SLC34A1
SLC4A7
SLC4A8
SLC9A3
SLCO1A2
SLCO3A1
ST6GALNAC2
TBC1D10A
TRPC4
TRPC5
YAP1
YES1
ZNF468
46 interacting genes:
AKT1
ANP32B
ATM
BAAT
BIRC3
CARD10
CARD11
CARD14
CARD19
CARD9
CASP9
CCDC180
CDC14B
CDK9
CHUK
COG6
FBP1
HEMGN
IKBKG
IL15RA
IRAK1
MALT1
MAP3K7
MIB2
NANS
NLRC4
OTULIN
PELI2
PRRG4
RASA1
RIPK2
RNF181
SLC20A1
SLC9A3R1
SOCS3
SRSF1
TGFB1
TLR4
TNFRSF10A
TNFRSF1A
TRADD
TRAF2
TRMO
UBE2N
UBE2V2
USHBP1
Entrez ID
9368
8915
HPRD ID
05406
04625
Ensembl ID
ENSG00000109062
ENSG00000142867
Uniprot IDs
O14745
A0A087WWW9
A2TDT2
O95999
PDB IDs
1G9O
1GQ4
1GQ5
1I92
1SGH
2D10
2JXO
2KJD
2KRG
2M0T
2M0U
2M0V
2OZF
4JL7
4LMM
4MPA
4N6X
4PQW
4Q3H
6RQR
2MB9
6BZE
6GK2
Enriched GO Terms of Interacting Partners
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