MS4A3 and IFITM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MS4A3	IFITM3
Description		membrane spanning 4-domains A3	interferon induced transmembrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Regulation Of Cell Cycle	Immune Response Response To Virus Negative Regulation Of Viral Transcription Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Negative Regulation Of Viral Genome Replication Negative Regulation Of Viral Entry Into Host Cell Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Neutrophil degranulation	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)	Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252)
Interacting Genes		39 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDK2 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1	27 interacting genes: ABHD16A AQP6 CD53 ELOVL2 ERGIC3 FAM210B FFAR2 FKBP7 GLP1R GPR37 GPRC5D KIR2DL3 LYPD5 MS4A3 NEDD4 OPRM1 PLP1 PTAFR REEP4 RETREG3 SGPL1 SLC10A1 SLC10A2 SLC16A7 TMEM14B TMEM86B VKORC1
Entrez ID		932	10410
HPRD ID		09403	05719
Ensembl ID		ENSG00000149516	ENSG00000142089
Uniprot IDs		Q96HJ5	Q01628
PDB IDs
Enriched GO Terms of Interacting Partners?
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