NREP and EIF3B

Number of citations of the paper that reports this interaction (PubMedID 25336651)
17

Data Source:
BioGRID (pull down)

		NREP	EIF3B
Description		neuronal regeneration related protein	eukaryotic translation initiation factor 3 subunit B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Synapse Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Molecular Adaptor Activity
	Biological Process	Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Axon Regeneration Regulation Of Neuron Differentiation	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Breast cancer ( 29059683) Gut microbiota relative abundance (Sutterella) ( 33208821) Hematocrit ( 32888494) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Platelet count ( 33545615 32888494 27863252) Plateletcrit ( 32888494 27863252) Reaction time ( 29844566) Red blood cell count ( 29403010 32888494) Thyroid cancer ( 28195142)	Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		5 interacting genes: ATM EEF1A1 EIF3B IGSF21 KMT2B	18 interacting genes: BHLHB9 BRCA1 EIF3A EIF3G EIF3I EIF3J EIF4G1 IL2RB LMO2 NDUFAB1 NF2 NREP PAIP1 PBX4 RPS6KB1 TBC1D23 TNNI1 UPF1
Entrez ID		9315	8662
HPRD ID		09545	06795
Ensembl ID		ENSG00000134986	ENSG00000106263
Uniprot IDs		Q16612	A0A024R821 A4D210 P55884
PDB IDs			2KRB 2NLW 5K1H 6YBT 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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