UBE2Q2 and RC3H2

Number of citations of the paper that reports this interaction (PubMedID 26489670)
13

Data Source:
BioGRID (pull down)

		UBE2Q2	RC3H2
Description		ubiquitin conjugating enzyme E2 Q2	ring finger and CCCH-type domains 2
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GO Annotations	Cellular Component	Nucleus Cytosol	P-body Cell Surface Cytoplasmic Stress Granule Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	DNA Binding RNA Binding Double-stranded RNA Binding MRNA Binding RNA Stem-loop Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Protein K48-linked Ubiquitination	Protein Polyubiquitination Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay B Cell Homeostasis Ubiquitin-dependent Protein Catabolic Process Post-embryonic Development Multicellular Organism Growth T Cell Proliferation T Cell Homeostasis Lung Alveolus Development Lymph Node Development Spleen Development T Cell Receptor Signaling Pathway Limb Development T Follicular Helper Cell Differentiation Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of MiRNA Metabolic Process
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Glomerular filtration rate ( 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Gout ( 33832965) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494) Triglyceride levels in HIV infection ( 33109212) Urate levels ( 31985003 23263486) Urate levels in obese individuals ( 25811787)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: BIRC2 BIRC3 ITCH MDM2 PCGF2 RC3H2 RNF111 RNF31 UBA1 UBC	14 interacting genes: KLHL6 TRIM8 UBC UBE2B UBE2D2 UBE2E2 UBE2E3 UBE2G2 UBE2I UBE2K UBE2N UBE2Q2 UBE2V1 UBE2V2
Entrez ID		92912	54542
HPRD ID		14294	14726
Ensembl ID		ENSG00000140367	ENSG00000056586
Uniprot IDs		Q8WVN8	A0A024R899 Q9HBD1
PDB IDs		1ZUO	4Z30 4Z31 4ZLC 4ZLD
Enriched GO Terms of Interacting Partners?
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