GORAB and CLN6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GORAB	CLN6
Description		golgin, RAB6 interacting	CLN6 transmembrane ER protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol	Nucleolus Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Membrane Raft
	Molecular Function	Protein Binding	Protein Binding Lysophosphatidic Acid Binding Protein Homodimerization Activity Sulfatide Binding
	Biological Process	Hair Follicle Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Non-motile Cilium Assembly	Ganglioside Metabolic Process Lysosome Organization Lysosomal Lumen Acidification Visual Perception Cholesterol Metabolic Process Protein Catabolic Process Glycosaminoglycan Metabolic Process Locomotion Involved In Locomotory Behavior Cellular Macromolecule Catabolic Process Positive Regulation Of Proteolysis
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Body shape index ( 34021172) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 27182965 28196072) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Major depressive disorder ( 23377640) Restless legs syndrome ( 29029846)
Interacting Genes		66 interacting genes: ABHD16A APOD APP ARF1 ARF3 ARF5 BCL2L1 BCL2L2 BET1L BNIP2 C3orf52 CD81 CES1 CLDN19 CLN6 CMTM7 CNIH2 COPB1 CTSA CXCL16 CXCL9 EMD FARSA FBXO7 GIMAP5 HOXD9 HSD17B7 ITGAM LPAR3 LRP10 MDM2 MS4A1 NEDD4L NKG7 NRM PAEP PLPP6 PTAFR PTPN9 RAB6A RCHY1 SCYL1 SEC22B SELENOK SNAPC5 STX12 STX8 TMEM11 TMEM120B TMEM128 TMEM14C TMEM187 TMEM19 TMEM229B TMEM60 TMEM86A TRAF3IP3 TSPAN33 VAMP3 VAMP5 VEZT VKORC1 VKORC1L1 WFDC2 ZFPL1 ZNF16	26 interacting genes: ARL13B CD79A CISD2 CLDN7 CLEC10A CPLX4 CREB3L1 CYBC1 EBAG9 EVI2B FAM209A FNDC9 GJA8 GORAB KIR2DL3 LIME1 LMNA LRRC25 RIC3 SLC22A23 SLC30A4 STX1A TEX264 TMEM139 TMEM237 TMPRSS2
Entrez ID		92344	54982
HPRD ID		12144	05991
Ensembl ID		ENSG00000120370	ENSG00000128973
Uniprot IDs		B3KQ87 Q5T7V8	A0A024R601 Q9NWW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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