RAB11B and RAB11FIP5

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vitro)

		RAB11B	RAB11FIP5
Description		RAB11B, member RAS oncogene family	RAB11 family interacting protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Synaptic Vesicle Phagocytic Vesicle Membrane Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane	Golgi Membrane Mitochondrion Mitochondrial Outer Membrane Early Endosome Golgi Apparatus Secretory Granule Transport Vesicle Membrane Early Endosome Membrane Centriolar Satellite Intracellular Membrane-bounded Organelle Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding	Protein Binding Small GTPase Binding Gamma-tubulin Binding
	Biological Process	Receptor Recycling Exocytosis Melanosome Transport Endocytic Recycling Transferrin Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Anion Transport Constitutive Secretory Pathway Regulated Exocytosis Cellular Response To Acidic PH Establishment Of Protein Localization To Membrane Amyloid-beta Clearance By Transcytosis Regulation Of Protein Localization To Cell Surface Regulation Of Endocytic Recycling	Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulated Exocytosis Negative Regulation Of Adiponectin Secretion Cellular Response To Acidic PH Regulation Of Protein Localization To Cell Surface
Pathways		TBC/RABGAPs RAB geranylgeranylation
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Non-word reading ( 30741946) Pediatric areal bone mineral density (spine vs radius & hip discordant skeletal phenotype) ( 29240982) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		12 interacting genes: APP IKBKG MEOX2 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SH3BP5L SREBF2 TYK2	11 interacting genes: ARF6 MOGS NAPG RAB11A RAB11B RAB11FIP4 RAB14 RAB25 REL RO60 YWHAG
Entrez ID		9230	26056
HPRD ID		05009	16117
Ensembl ID		ENSG00000185236	ENSG00000135631
Uniprot IDs		Q15907	Q9BXF6 Q9UFM0
PDB IDs		2F9L 2F9M 4OJK
Enriched GO Terms of Interacting Partners?
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