KCNAB3 and GMDS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KCNAB3	GMDS
Description		potassium voltage-gated channel subfamily A regulatory beta subunit 3	GDP-mannose 4,6-dehydratase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Transmembrane Transporter Binding D-threo-aldose 1-dehydrogenase Activity	Protein Binding GDP-mannose 4,6-dehydratase Activity Identical Protein Binding NADP+ Binding
	Biological Process	Potassium Ion Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	Notch Signaling Pathway GDP-mannose Metabolic Process 'de Novo' GDP-L-fucose Biosynthetic Process
Pathways		Voltage gated Potassium channels	GDP-fucose biosynthesis
Drugs			Guanosine-5'-Diphosphate-Rhamnose Guanosine-5'-Diphosphate
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Refractive error ( 32231278) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Anthropometric traits (multi-trait analysis) ( 30166351) Caudate nucleus volume ( 21502949) Coronary artery disease ( 29212778) Daytime sleep phenotypes ( 27126917) Fasting glucose ( 34074324) Fish intake frequency ( 31320941) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (low intraocular pressure) ( 33627673) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935 25173105) Haemorrhoidal disease ( 33888516) HDL cholesterol levels in HIV infection ( 33109212) Heel bone mineral density ( 30598549) Height ( 31562340) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Hip circumference adjusted for BMI ( 34021172 25673412) Impulsivity (non-planning) ( 30718321) Intraocular pressure ( 29617998 29785010 31959993 30054594) Iris heterochromicity ( 30895295) Late-onset myasthenia gravis ( 26562150) Medication use (diuretics) ( 31015401) Monobrow ( 27182965) Monobrow thickness ( 26926045) Myocardial infarction ( 33532862) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Orofacial clefts ( 33137956) Pulse pressure ( 30578418) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278) Response to platinum-based agents ( 22020760) Reticulocyte count ( 32888494) Sub-cortical grey matter volume ( 31530798) Urate levels ( 31578528) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		5 interacting genes: APP GMDS NEDD4L PLEKHF2 ZBTB14	2 interacting genes: KCNAB3 NTAQ1
Entrez ID		9196	2762
HPRD ID		04983	11925
Ensembl ID		ENSG00000170049	ENSG00000112699
Uniprot IDs		O43448	O60547
PDB IDs			1T2A 5IN4 5IN5 6GPJ 6GPK 6GPL 6Q94
Enriched GO Terms of Interacting Partners?
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