AP4M1 and USP47

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AP4M1	USP47
Description		adaptor related protein complex 4 subunit mu 1	ubiquitin specific peptidase 47
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity Protein Domain Specific Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding WD40-repeat Domain Binding Deubiquitinase Activity
	Biological Process	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Protein Transmembrane Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane	Base-excision Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Response To Xenobiotic Stimulus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Positive Regulation Of Cell Growth Regulation Of Protein Stability Cellular Response To UV Monoubiquitinated Protein Deubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		Lysosome Vesicle Biogenesis	Ub-specific processing proteases
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		15 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 PMPCB TGOLN2 USP47 ZBTB22	7 interacting genes: AP4M1 MED29 MED9 PLA2G2A RPS2 SNCA UBC
Entrez ID		9179	55031
HPRD ID		03803	11668
Ensembl ID		ENSG00000221838	ENSG00000170242
Uniprot IDs		C9JC87 O00189	Q68D97 Q96K76
PDB IDs		3L81 4MDR
Enriched GO Terms of Interacting Partners?
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