LONRF1 and IKZF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		LONRF1	IKZF2
Description		LON peptidase N-terminal domain and ring finger 1	IKAROS family zinc finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus
	Molecular Function	Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Molecular_function DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Colorectal cancer (diet interaction) ( 24743840) HDL cholesterol levels ( 32203549)	C-reactive protein levels ( 30388399) Eosinophil counts ( 29403010 19198610 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Estimated glomerular filtration rate ( 31451708) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Selective IgA deficiency ( 27723758) Squamous cell lung carcinoma ( 28604730) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 26502338) Systemic sclerosis ( 29293537) Type 2 diabetes ( 32499647)
Interacting Genes		96 interacting genes: ADAMTSL4 ALAS1 AP2B1 ATG9A AVPI1 BHLHB9 BRCA1 BYSL C4orf17 CALCOCO2 CBLL2 CDKN2D CFP CRX CYSRT1 DVL3 EFHC2 FLACC1 GABPB2 GORASP1 GORASP2 HLX HOXA1 HSPB1 IHO1 IKZF2 IKZF3 IQCF2 KAT5 KATNBL1 KCTD21 KCTD9 KHDC1 KRT31 KRT35 KRT75 KRTAP1-3 KRTAP13-1 KRTAP13-3 KRTAP19-6 KRTAP19-7 KRTAP3-3 KRTAP6-1 LGALS9B LHX2 LHX4 LNX1 MAGED1 MGAT5B MID2 MRPL38 MTMR3 MYOZ3 NR4A1 NTAQ1 OOEP PATZ1 PAX5 PAX6 PAX8 PICK1 PLSCR1 POU6F2 PPP1R3C PRDM16 PRDM6 PRR35 PSMA1 RBPMS RIMBP3C RPRD1A SFN SLU7 SPRY2 STAU1 STX11 TASOR2 TBX19 TRAF2 TRIM27 TRIM42 TRIM8 TRIM9 UBE2I UBE2L6 UCHL3 USP2 VGLL1 WDR83 XIAP YPEL3 ZFP90 ZNF426 ZNF653 ZNF774 ZNHIT2	10 interacting genes: AQP1 CTBP1 CTBP2 HDAC4 IKZF1 IKZF4 IKZF5 LONRF1 SPAG16 TCEANC
Entrez ID		91694	22807
HPRD ID		08674	05872
Ensembl ID		ENSG00000154359	ENSG00000030419
Uniprot IDs		Q17RB8	A0A024R3Z4 Q9UKS7
PDB IDs
Enriched GO Terms of Interacting Partners?
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