BTF3L4 and SMYD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BTF3L4	SMYD2
Description		basic transcription factor 3 like 4	SET and MYND domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	RNA Polymerase II Complex Binding P53 Binding Protein Binding Lysine N-methyltransferase Activity Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity Metal Ion Binding Histone Methyltransferase Activity (H3-K36 Specific)
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Heart Development Negative Regulation Of Cell Population Proliferation Histone H3-K36 Methylation Peptidyl-lysine Monomethylation Peptidyl-lysine Dimethylation Histone Lysine Methylation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator
Pathways			PKMTs methylate histone lysines Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS			Abdominal aortic aneurysm ( 27899403) Age at first sexual intercourse ( 34211149) Diverticular disease ( 30177863) Rheumatic heart disease ( 34106200) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		5 interacting genes: NOTCH3 SMYD2 TXLNA TXLNB ZYG11B	7 interacting genes: BTF3L4 ESR1 H3C14 HSP90AA1 RB1 SNX11 TP53
Entrez ID		91408	56950
HPRD ID		17521	15406
Ensembl ID		ENSG00000134717	ENSG00000143499
Uniprot IDs		Q96K17	Q9NRG4
PDB IDs			3RIB 3S7B 3S7D 3S7F 3S7J 3TG4 3TG5 4O6F 4WUY 4YND 5ARF 5ARG 5KJK 5KJL 5KJM 5KJN 5V3H 5WCG 6CBX 6CBY 6MON 6N3G
Enriched GO Terms of Interacting Partners?
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