PIGQ and PIGA

Number of citations of the paper that reports this interaction (PubMedID 9463366)
57

Data Source:
HPRD (in vitro)

		PIGQ	PIGA
Description		phosphatidylinositol glycan anchor biosynthesis class Q	phosphatidylinositol glycan anchor biosynthesis class A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding UDP-glycosyltransferase Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Carbohydrate Metabolic Process GPI Anchor Biosynthetic Process	GPI Anchor Biosynthetic Process Positive Regulation Of Metabolic Process Preassembly Of GPI Anchor In ER Membrane Cellular Response To Leukemia Inhibitory Factor
Pathways			Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Disc degeneration (lumbar) ( 22993228) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		4 interacting genes: PIGA PIGC PIGH SMAD1	5 interacting genes: DPM2 LRP1 PIGH PIGQ PIGY
Entrez ID		9091	5277
HPRD ID		09307	02410
Ensembl ID		ENSG00000007541	ENSG00000165195
Uniprot IDs		B2RAU6 Q9BRB3	A0A2K4ZA02 P37287
PDB IDs
Enriched GO Terms of Interacting Partners?
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