PRC1 and KIF4A

Number of citations of the paper that reports this interaction (PubMedID 15297875)
135

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down, two hybrid)

		PRC1	KIF4A
Description		protein regulator of cytokinesis 1	kinesin family member 4A
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring Mitotic Spindle Midzone	Nucleoplasm Chromosome Cytoplasm Cytosol Spindle Microtubule Membrane Nuclear Matrix Midbody Axon Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Mitotic Spindle Elongation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Positive Regulation Of Cell Population Proliferation Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division	Mitotic Cytokinesis Organelle Organization Mitotic Spindle Organization Anterograde Axonal Transport Mitotic Spindle Midzone Assembly
Pathways		RHO GTPases activate CIT	MHC class II antigen presentation Recycling pathway of L1 Recycling pathway of L1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Breast cancer ( 29059683 25038754) Mean platelet volume ( 32888494 27863252) Multisite chronic pain ( 33830993 31194737) Red cell distribution width ( 32888494) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 32499647 20581827 30718926 28869590)
Interacting Genes		30 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 CINP FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 MAT2A NDEL1 OGT PCM1 PKIA PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 SUMO2 TRIM37 USHBP1 YWHAE	8 interacting genes: APP DNMT3B HMG20B PDZD11 PRC1 SUMO2 TAF1 TTF2
Entrez ID		9055	24137
HPRD ID		17899	06606
Ensembl ID		ENSG00000198901	ENSG00000090889
Uniprot IDs		A0A024RC67 O43663	O95239 Q59HG1
PDB IDs		3NRX 3NRY 4L3I 4L6Y 5KMG	6OYL
Enriched GO Terms of Interacting Partners?
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