KNSTRN and MAPRE3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		KNSTRN	MAPRE3
Description		kinetochore localized astrin (SPAG5) binding protein	microtubule associated protein RP/EB family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Ruffle Nucleus Cytoplasm Plasma Membrane Centriolar Satellite Microtubule Plus-end Mitotic Spindle	Cytoplasm Microtubule Organizing Center Midbody Microtubule Plus-end Spindle Midzone Mitotic Spindle Astral Microtubule End
	Molecular Function	Protein Binding Protein Homodimerization Activity Microtubule Plus-end Binding	Protein Binding Microtubule Binding Protein C-terminus Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Mitotic Sister Chromatid Segregation Microtubule Cytoskeleton Organization Spindle Organization Chromosome Segregation Cell Migration Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cellular Response To Epidermal Growth Factor Stimulus	Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription, DNA-templated Spindle Assembly Cell Division Positive Regulation Of Microtubule Plus-end Binding Protein Localization To Microtubule Plus-end
Pathways
Drugs
Diseases
GWAS		Heschl's gyrus morphology ( 25130324) Malaria ( 31844061)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Leftâ€“right brain asymmetry ( 33723403) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		17 interacting genes: ABI2 BEX2 CHMP1B CLU HSPB1 IFT20 MAPK6 MAPRE1 MAPRE3 MPHOSPH6 NUPR1 OIP5 PALS2 PPL SGF29 WASHC3 ZDHHC17	57 interacting genes: ANKRD1 APC2 AURKA AURKB C20orf202 C4orf45 CCSER1 CHRDL2 CLASP1 CRTAC1 DCTN2 DDIT4L DOK4 EIF4E2 FAM161B FOXD4L1 FOXD4L4 FXR2 GAS2L2 GTF2F2 GTSE1 HROB IKZF1 JUN KIF19 KLHDC7B KNSTRN LAP3 LHX4 LMO2 MAPRE2 MARCHF7 MEOX2 MRPL12 PDE4DIP PICK1 POU4F1 PSMA1 PSMB1 PSRC1 RAB1A REL SDCBP SIAH1 SLAIN1 SPDYE2 SPDYE2B TEX43 TLE5 TRAIP TRIM14 TXN2 YAF2 ZC2HC1A ZC2HC1C ZNF526 ZNF547
Entrez ID		90417	22924
HPRD ID		12669	16156
Ensembl ID		ENSG00000128944	ENSG00000084764
Uniprot IDs		Q9Y448	Q9UPY8
PDB IDs			1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7
Enriched GO Terms of Interacting Partners?
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