BAZ1B and CDT1

Number of citations of the paper that reports this interaction (PubMedID 18162579)
30

Data Source:
BioGRID (pull down)

		BAZ1B	CDT1
Description		bromodomain adjacent to zinc finger domain 1B	chromatin licensing and DNA replication factor 1
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GO Annotations	Cellular Component	Condensed Chromosome Nucleoplasm Pericentric Heterochromatin Nuclear Body Nuclear Replication Fork	Kinetochore Nucleus Nucleoplasm Cytosol Nuclear Body
	Molecular Function	Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Histone Binding	DNA Binding Chromatin Binding Protein Binding DNA Polymerase Binding
	Biological Process	Chromatin Assembly Or Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation	DNA Replication Checkpoint Signaling Mitotic Cell Cycle Chromosome Segregation Regulation Of DNA-dependent DNA Replication Initiation Positive Regulation Of Protein-containing Complex Assembly Regulation Of Chromosome Organization Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of Chromatin Binding Positive Regulation Of DNA Replication Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Organization DNA Replication Preinitiation Complex Assembly Response To Sorbitol Deactivation Of Mitotic Spindle Assembly Checkpoint Regulation Of DNA Replication Origin Binding Negative Regulation Of Protein Localization To Kinetochore Positive Regulation Of Protein Localization To Kinetochore Positive Regulation Of DNA-dependent DNA Replication
Pathways		B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	CDT1 association with the CDC6:ORC:origin complex Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex G1/S-Specific Transcription
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 33730874) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Hip index ( 34021172) Hypertriglyceridemia ( 23505323) Hyperuricemia ( 29124443) Lamb consumption ( 32066663) Malaria ( 31844061) Meat-related diet ( 32066663) Metabolic syndrome ( 31589552) Migraine ( 27182965) Non-oily fish consumption ( 32066663) Platelet count ( 32888494) Protein C levels ( 20802025) Pursuit maintenance gain ( 29064472) Serum alkaline phosphatase levels ( 33339817) Serum uric acid levels ( 30993211) Triglyceride levels ( 32203549) Triglyceride levels x fish oil supplementation interaction (2df) ( 33760818) Triglycerides ( 20864672) Urate levels ( 31985003 23263486) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Glycated hemoglobin levels ( 28898252) Hair color ( 26926045) Hemoglobin A1c levels ( 29403010) Mean corpuscular hemoglobin concentration ( 29403010 20139978 28017375) Mean corpuscular volume ( 29403010)
Interacting Genes		15 interacting genes: CDT1 H2AX KANSL1 KAT8 MAILR MTNR1A MYO1C NR4A2 PCNA SIRT1 SMARCA1 SMARCA5 SMARCC2 SMARCE1 SUMO2	29 interacting genes: ANAPC7 BAZ1B CCNA2 CCNB1 CDC20 CDC23 CDC5L CDC6 CDK1 CDK2 COL6A3 DTL EP300 FBXO31 FOXO3 FZR1 GMNN KAT2B MAPK14 MCM2 MCM4 MCM6 NPM1 ORC1 ORC2 PCNA SKP2 SMARCA5 UBB
Entrez ID		9031	81620
HPRD ID		10416	06900
Ensembl ID		ENSG00000009954	ENSG00000167513
Uniprot IDs		Q9UIG0	Q9H211
PDB IDs		1F62 5NNF	2LE8 2WVR 6QCG
Enriched GO Terms of Interacting Partners?
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