TAF1B and ACADVL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TAF1B	ACADVL
Description		TATA-box binding protein associated factor, RNA polymerase I subunit B	acyl-CoA dehydrogenase very long chain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus RNA Polymerase I Core Factor Complex	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Mitochondrial Membrane Mitochondrial Nucleoid
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding Protein Binding TBP-class Protein Binding Metal Ion Binding	Fatty-acyl-CoA Binding Acyl-CoA Dehydrogenase Activity Long-chain-acyl-CoA Dehydrogenase Activity Protein Binding Very-long-chain-acyl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Transcription, DNA-templated Nucleolar Large RRNA Transcription By RNA Polymerase I	Temperature Homeostasis Response To Cold Energy Derivation By Oxidation Of Organic Compounds Epithelial Cell Differentiation Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Negative Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Fatty Acid Oxidation Regulation Of Cholesterol Metabolic Process
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	XBP1(S) activates chaperone genes Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Egg allergy (maternal genetic effects) ( 29489655) Non-response to selective serotonin reuptake inhibitors and depression ( 27622933) Nonsyndromic cleft lip with cleft palate ( 28232668) Prostate cancer ( 23535732)	Metabolite levels ( 23823483)
Interacting Genes		28 interacting genes: ACADVL APP CALR EP300 ESR1 H2AC20 H2BC21 H3C1 H4C1 MEOX2 MYC NAPB NEDD4 NEDD4L PGR RRM2 RRN3 RXRA SRPK1 TAF1A TAF1C TAF1D TBP THAP7 TP53 TRB TRIM24 UBTF	5 interacting genes: GPHN LINC01554 RPSA SOCS3 TAF1B
Entrez ID		9014	37
HPRD ID		05363	01940
Ensembl ID		ENSG00000115750	ENSG00000072778
Uniprot IDs		Q53T94	B3KPA6 P49748
PDB IDs			2UXW 3B96
Enriched GO Terms of Interacting Partners?
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