CCDC120 and CYTH3

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		CCDC120	CYTH3
Description		coiled-coil domain containing 120	cytohesin 3
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Centriole Growth Cone Centriolar Subdistal Appendage	Golgi Membrane Ruffle Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Protein Localization Microtubule Anchoring At Centrosome	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity
Pathways			Intra-Golgi traffic
Drugs			Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS			Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Shigella-associated diarrhea ( 33649051)
Interacting Genes		106 interacting genes: AKAP8L ARID5A ATP23 BCAS2 BHLHB9 BLZF1 BRCA1 C1orf109 CADPS CALCOCO2 CCDC102B CCDC13 CCDC136 CCDC57 CCDC85B CDR2 CEP170P1 CEP55 CKS1B CNFN COG6 CTBP2 CYSRT1 CYTH1 CYTH2 CYTH3 CYTH4 DAZAP2 EFHC2 EIF3F FCHSD2 FOS FOSL1 FSD2 GOLGA2 GOLGA6L9 HNRNPH1 HOMER3 HOXA1 HSF2BP IFT88 IHO1 INTS11 KASH5 KRT15 KRT31 KRT34 KRT35 KRT38 KRT40 KRTAP13-3 KRTAP19-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 LMNA LMNB2 LMO4 LZTS1 MAGED1 MDFI MED11 METTL27 MID2 MIIP MIPOL1 MKRN3 MRPL38 MTUS2 MYOG NCK2 NEK6 NOTO NXF1 PKP2 PLA2G10 PLAGL2 PLEKHG4 POU2AF1 PRDM6 RABEP1 RBPMS RERE RINT1 RUSC1 SFI1 SMARCB1 SORBS3 SPAG8 STX11 TFIP11 TLE5 TP53BP1 TRAF1 TRIM42 TRIM55 TRIM63 TRIP6 TSC1 TSGA10IP USHBP1 ZDHHC17 ZIM2 ZMAT5 ZNF648 ZRANB1	12 interacting genes: ARFIP2 CALCOCO1 CCDC120 CNKSR1 CYTIP FRMD4B IFI35 INAVA IPCEF1 PIK3CA SYCE1 TAMALIN
Entrez ID		90060	9265
HPRD ID		06595	05469
Ensembl ID		ENSG00000147144	ENSG00000008256
Uniprot IDs		Q96HB5	O43739
PDB IDs			4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?
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