CCNG1 and PLEKHA4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CCNG1	PLEKHA4
Description		cyclin G1	pleckstrin homology domain containing A4
Image		No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm	Cytoplasm Plasma Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Phase Transition Cell Division	Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways		Regulation of TP53 Degradation	Synthesis of PIPs at the plasma membrane
Drugs			Inositol 1,3,4,5-Tetrakisphosphate
Diseases
GWAS		atherosclerosis-relevant cellular traits (vascular smooth muscle cells) ( 33040646) HIV progression (CD4 and viral load) ( 28132517) Metabolite levels ( 31628463) Plasma anti-thyroglobulin levels ( 29678681) Severe influenza A (H1N1) infection ( 26379185)	High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)
Interacting Genes		28 interacting genes: APP CBY2 CCDC125 CDK5 CDKN2A GAK GAS8 GRN HMBOX1 KRT40 KRTAP10-7 LMNA LTBP3 LZTS2 MDM2 MT-CO2 NFATC4 PAK5 PLEKHA4 PNMA1 PPP2CA PTPA RBPMS SHKBP1 TFAP2C TFIP11 TNIP1 TP53	10 interacting genes: ABL1 ATP5MG CCNG1 EEF1G KAT5 KLHL12 LRIF1 MEI4 SETDB1 SHANK3
Entrez ID		900	57664
HPRD ID		03345	09683
Ensembl ID		ENSG00000113328	ENSG00000105559
Uniprot IDs		P51959	Q9H4M7
PDB IDs			1UPQ 1UPR
Enriched GO Terms of Interacting Partners?
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