FATE1 and CD83

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FATE1	CD83
Description		fetal and adult testis expressed 1	CD83 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondria-associated Endoplasmic Reticulum Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration	Defense Response Humoral Immune Response Signal Transduction Response To Organic Cyclic Compound Negative Regulation Of Interleukin-4 Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-2 Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Systemising ( 31508503)	Breast cancer and/or colorectal cancer ( 29698419) California verbal learning test score ( 31596458) Chronotype ( 30696823) Obesity-related traits ( 23251661) Response to tofacitinib treatment (herpes zoster) ( 33455090) Response to tofacitinib treatment (herpes zoster)(time to event) ( 33455090) Response to tofacitinib treatment in psoriasis (herpes zoster) ( 33455090) Response to tofacitinib treatment in psoriasis (herpes zoster)(time to event) ( 33455090) Rheumatoid arthritis ( 30423114 22446963 24390342)
Interacting Genes		99 interacting genes: AGTRAP APOL3 AQP9 ASGR2 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 C1QL4 CALN1 CCDC70 CD302 CD79A CD83 CDC37 CERS4 CREB3L3 CSF2RA CTRL CXCR1 CXCR3 DCTN5 DNAJC30 EMD FAM177A1 FAM209A FRMD8 GIMAP5 GINM1 GOSR2 GPR25 HSD17B13 INPP5K KASH5 KCNS2 LMNA LNPEP LRRC25 MARCHF2 MARCHF3 MARCHF5 MARVELD2 MFF MOSPD3 MR1 NDUFB11 NRG4 NRSN1 OCLN OTOP2 PIN4 PKMYT1 PLP2 PRRG2 RBFA RIC3 RNF183 RPRM RTP2 SCAMP5 SEC22A SEC22C SEC23A SEC23B SLC38A1 SLC41A2 SLC7A1 SLC7A14 SMIM14 SNAP47 SSMEM1 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM179B TMEM201 TMEM74 TRAF2 TRAF3IP3 UBE2I UNC93B1 USHBP1 USP20 VSIG4 VSTM1 YIPF2 YIPF4 ZCCHC12 ZFPL1	10 interacting genes: EIF4E FAM8A1 FATE1 GCM2 GMPR KIF13A NOL7 PAPSS2 SACS SPP1
Entrez ID		89885	9308
HPRD ID		02346	05170
Ensembl ID		ENSG00000147378	ENSG00000112149
Uniprot IDs		Q969F0	A0A087WX61 Q01151
PDB IDs			5MIX 5MJ0 5MJ1 5MJ2
Enriched GO Terms of Interacting Partners?
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