KLHL6 and PPP1R1B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		KLHL6	PPP1R1B
Description		kelch like family member 6	protein phosphatase 1 regulatory inhibitor subunit 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Cytosol Neuronal Cell Body Dendritic Spine Neck Dendritic Spine Head Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Kinase Inhibitor Activity CAMP-dependent Protein Kinase Inhibitor Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity D1 Dopamine Receptor Binding D2 Dopamine Receptor Binding D3 Dopamine Receptor Binding D4 Dopamine Receptor Binding D5 Dopamine Receptor Binding
	Biological Process	Germinal Center Formation B Cell Receptor Signaling Pathway	Response To Amphetamine Transcription, DNA-templated Signal Transduction Memory Negative Regulation Of Female Receptivity Locomotory Behavior Visual Learning Negative Regulation Of Phosphoprotein Phosphatase Activity Response To Nicotine Intracellular Signal Transduction Response To Morphine Behavioral Response To Cocaine Cellular Response To Cocaine Negative Regulation Of CAMP-dependent Protein Kinase Activity
Pathways			DARPP-32 events DARPP-32 events
Drugs
Diseases
GWAS		Youthful appearance (self-reported) ( 32339537)	Asthma ( 31959851 31619474) Estimated glomerular filtration rate ( 31015462) Hematocrit ( 32888494) Hemoglobin ( 32888494) Refractive error ( 32231278) Ulcerative colitis ( 20228799)
Interacting Genes		7 interacting genes: BYSL CRY2 FH PPP1R1B RC3H2 SBDS TMPO	10 interacting genes: CDK5 CSNK2A1 CSNK2A2 DLGAP4 FBXL20 KLHL6 PPP1CA PRKACA ROBO2 TFCP2
Entrez ID		89857	84152
HPRD ID		10035	05097
Ensembl ID		ENSG00000172578	ENSG00000131771
Uniprot IDs		Q8WZ60	A0A024R1R3 B3KVQ9 Q9UD71
PDB IDs
Enriched GO Terms of Interacting Partners?
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