WASL and CORO7

Number of citations of the paper that reports this interaction (PubMedID 27143109)
10

Data Source:
BioGRID (pull down, affinity chromatography technology)

		WASL	CORO7
Description		WASP like actin nucleation promoting factor	coronin 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Actin Filament Plasma Membrane Actin Cytoskeleton Lamellipodium Actin Cap Endocytic Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	Actin Binding Protein Binding GTPase Regulator Activity	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Vesicle Budding From Membrane Actin Polymerization Or Depolymerization Response To Bacterium Vesicle Organization Actin Filament Polymerization Actin Filament-based Movement Vesicle Transport Along Actin Filament Regulation Of Protein Localization Cellular Protein-containing Complex Localization Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Catalytic Activity Cell Division Positive Regulation Of Filopodium Assembly Spindle Localization Dendritic Spine Morphogenesis Protein-containing Complex Assembly Negative Regulation Of Membrane Tubulation Positive Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Lymphocyte Migration Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Golgi To Endosome Transport Actin Filament Organization Protein Transport Actin Filament Polymerization
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation NOSTRIN mediated eNOS trafficking Nephrin family interactions EPHB-mediated forward signaling EPHB-mediated forward signaling DCC mediated attractive signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOV GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Platelet count ( 22139419 27863252) Plateletcrit ( 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Body shape index ( 34021172) Eosinophil counts ( 32888494) Erectile dysfunction ( 30583798) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172 25673412) Lymphocyte counts ( 32888494) Schizophrenia ( 28991256) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 30389748) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		65 interacting genes: AASS ABI2 ABL1 ACTG1 ACTR2 ACTR3 APBB1 APP ARHGAP12 ARPC3 ARPC4 BIN1 CDC42 CORO7 CTTN DNMBP EGFR EVL FCHSD2 FNBP1 FNBP1L GNAL GRB2 HP HSP90AA1 HSP90AB1 IPO5 ITCH ITGB1BP2 ITSN1 ITSN2 LCK NCK1 NCK2 NCKIPSD OSTF1 PACSIN1 PACSIN2 PACSIN3 PFN1 PRMT2 PRPF40A PSTPIP1 PTK6 RHOJ RHOQ RNF8 RPL7AP66 SDCBP SH3GL3 SH3RF1 SNX9 SORBS2 SRC TNNT3 TRIP10 UBASH3A UBASH3B VASP VIPR1 WIPF1 WIPF2 WIPF3 WWP1 ZNF395	9 interacting genes: ACTB AP1M1 AP2M1 EPS15 KLHL20 SRC TOB1 WASL ZRANB1
Entrez ID		8976	79585
HPRD ID		05448	07975
Ensembl ID		ENSG00000106299	ENSG00000262246
Uniprot IDs		O00401	P57737
PDB IDs		2FF3 2LNH 2VCP 4CC2 4CC7
Enriched GO Terms of Interacting Partners?
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