KYNU and CT55

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KYNU	CT55
Description		kynureninase	cancer/testis antigen 55
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Pyridoxal Phosphate Binding Kynureninase Activity Protein Homodimerization Activity 3-hydroxykynureninase Activity	Protein Binding
	Biological Process	Tryptophan Catabolic Process Aging NAD Biosynthetic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Quinolinate Biosynthetic Process Response To Interferon-gamma 'de Novo' NAD Biosynthetic Process From Tryptophan Response To Vitamin B6 Anthranilate Metabolic Process L-kynurenine Catabolic Process
Pathways		Tryptophan catabolism
Drugs		Pyridoxal phosphate Alanine m-Hydroxyhippuric acid
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Blood protein levels ( 30072576 29875488 28240269) Cataracts ( 34127677) Empathy quotient ( 29527006) Glomerular filtration rate in chronic kidney disease ( 26420894) Neurological blood protein biomarker levels ( 31320639) Platelet count ( 32888494) Response to SSRI (symptom remission) ( 29160301) Toenail selenium levels ( 25343990)
Interacting Genes		9 interacting genes: CDC42 CT55 CTBP2 FAM86C1P LMO4 MCCD1 MYOZ3 PIP4K2B RASSF3	32 interacting genes: BFSP2 BHLHB9 C1orf109 C2CD6 CABP5 CPNE2 DES EXOC7 FAAP20 GFAP KIAA0753 KLC3 KLHL42 KYNU LYPLAL1 MBD3 MEMO1 MEOX2 P4HA3 PAX7 PIH1D2 PRPH SAMD11 SHC3 SNF8 SPG21 TFIP11 TLE5 TXLNB VIM ZNF177 ZNF559-ZNF177
Entrez ID		8942	54967
HPRD ID		08940	06534
Ensembl ID		ENSG00000115919	ENSG00000169551
Uniprot IDs		Q16719	Q8WUE5
PDB IDs		2HZP 3E9K
Enriched GO Terms of Interacting Partners?
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