LDB1 and SSBP4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		LDB1	SSBP4
Description		LIM domain binding 1	single stranded DNA binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cell Leading Edge Protein-containing Complex Beta-catenin-TCF Complex	Nucleus
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding	Single-stranded DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Nervous System Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of Cell Migration Regulation Of Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Mesendoderm Development Regulation Of Focal Adhesion Assembly	Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494) Pulse pressure ( 30578418)	Alzheimer's disease (late onset) ( 30820047) Basophil count ( 32888494) Breast cancer ( 23535729) Intake of total sugars ( 31005972) Monocyte count ( 27863252) Systemic lupus erythematosus ( 33272962 33536424 28714469)
Interacting Genes		34 interacting genes: ARTN ATXN1 CTDSP1 DNMT3L ESR1 IDI2 IRAK3 ISL1 ISL2 LHX1 LHX2 LHX3 LHX4 LHX6 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP UPF1	8 interacting genes: IL36RN LDB1 LDB2 MYO15B PIK3R3 PIN1 SPG21 TFAP2B
Entrez ID		8861	170463
HPRD ID		09144	09579
Ensembl ID		ENSG00000198728	ENSG00000130511
Uniprot IDs		A0A6E1WJ75 Q86U70	Q9BWG4
PDB IDs		2XJY 2XJZ 2YPA 6TYD
Enriched GO Terms of Interacting Partners?
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