PEX11A and AMBRA1

		PEX11A	AMBRA1
Description		peroxisomal biogenesis factor 11 alpha	autophagy and beclin 1 regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Protein-containing Complex	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Autophagosome Cytosol Axoneme Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Ubiquitin Protein Ligase Binding GTPase Binding
	Biological Process	Peroxisome Organization Signal Transduction Peroxisome Membrane Biogenesis Peroxisome Fission Regulation Of Peroxisome Size Brown Fat Cell Differentiation	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Nervous System Development Cell Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Response To Mitochondrial Depolarisation
Pathways		PPARA activates gene expression	Macroautophagy
Drugs
Diseases
GWAS		Height ( 31562340) Two-hour glucose ( 34059833)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 28552196) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Immunoglobulin A ( 20694011) Insulin-related traits (multivariate analysis) ( 32002517) Normal facial asymmetry (angle of deformation score) ( 30631343) Schizophrenia ( 28991256 29483656 30285260) Selective IgA deficiency ( 27723758)
Interacting Genes		3 interacting genes: AMBRA1 FES PEX19	20 interacting genes: ALX4 BECN1 CHUK CREM CUL4B GABARAP GABARAPL1 GABARAPL2 HSD17B12 KBTBD4 MAP1LC3A MAP1LC3B MAP1LC3C MTCH2 MTOR PEX11A RNF2 SLC35C1 SNCA UBE2D3
Entrez ID		8800	55626
HPRD ID		04843	10975
Ensembl ID		ENSG00000166821	ENSG00000110497
Uniprot IDs		B2R8C6 B4DMF6 O75192	A0A075B6T1 Q9C0C7
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?