FBP2 and MLH3

Number of citations of the paper that reports this interaction (PubMedID 24412244)
2

Data Source:
BioGRID (two hybrid)

		FBP2	MLH3
Description		fructose-bisphosphatase 2	mutL homolog 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Z Disc Cell Junction Extracellular Exosome	Synaptonemal Complex Male Germ Cell Nucleus Nucleus Nucleoplasm Chiasma Mismatch Repair Complex
	Molecular Function	Protein Binding Fructose 1,6-bisphosphate 1-phosphatase Activity Identical Protein Binding Metal Ion Binding	Chromatin Binding Satellite DNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Centromeric DNA Binding Mismatched DNA Binding
	Biological Process	Sucrose Biosynthetic Process Fructose Metabolic Process Fructose 6-phosphate Metabolic Process Gluconeogenesis Dephosphorylation Fructose 1,6-bisphosphate Metabolic Process	Mismatch Repair Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Female Meiosis I Protein Localization
Pathways		Gluconeogenesis	Meiotic recombination
Drugs
Diseases
GWAS		Caudal middle frontal gyrus volume ( 31530798) Colorectal cancer (alcohol consumption interaction) ( 27723779) Height ( 19893584)	Inflammatory bowel disease ( 23128233) Mood instability ( 29187730) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: AURKA AXIN2 BMPR1A BUB1 CHD3 CTNNA1 DLC1 FBP1 FBXW7 MAP2K4 MLH3 MSH2 NFRKB NRAS PDGFRL PIK3CA RB1 SMAD2 SMAD4 SRC STK11	48 interacting genes: AKT1 ALDOB ANP32B AOPEP AR BAAT CCDC180 CDC14B CDK8 CTSV CYLC2 DVL1 EXO1 FANCC FBP1 FBP2 FRAT2 GALNT12 HEMGN HRAS HSD17B3 IGFBP3 LEF1 MAP2K1 MLH1 MSANTD3 MSH4 MSH5 NANS PCNA PPP2CB PPP3R2 RASA1 SEC61B SFRP2 SMAD1 STX17 TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRIM55 TRIM63 TSTD2 XPA ZDHHC17 ZNF510
Entrez ID		8789	27030
HPRD ID		04322	05094
Ensembl ID		ENSG00000130957	ENSG00000119684
Uniprot IDs		O00757	Q2M1Z1 Q9UHC1
PDB IDs		3IFA 3IFC 4HE0 4HE1 4HE2 5ET5 5ET6 5ET7 5ET8 5K54 5K55 5K56 5L0A 5Q0C
Enriched GO Terms of Interacting Partners?
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