RIOK3 and TULP3

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		RIOK3	TULP3
Description		RIO kinase 3	TUB like protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Preribosome, Small Subunit Precursor	Extracellular Region Nucleus Nucleoplasm Nucleolus Plasma Membrane Cilium Axoneme Ciliary Base 9+0 Non-motile Cilium
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Caspase Binding Protein Serine Kinase Activity	G Protein-coupled Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Enzyme Binding Phosphatidylinositol Binding Protein-containing Complex Binding Intraciliary Transport Particle A Binding
	Biological Process	Protein Phosphorylation Chromosome Segregation Maturation Of SSU-rRNA Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Interferon-beta Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus Cellular Response To DsRNA Cellular Response To Virus Cellular Response To DsDNA	Neural Tube Closure Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Anterior/posterior Pattern Specification Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Central Nervous System Neuron Differentiation Embryonic Camera-type Eye Development Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Bone Development Bronchus Morphogenesis Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Protein Localization To Cilium Ganglion Development Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Hedgehog 'off' state
Drugs		Fostamatinib
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Poultry consumption ( 32066663) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Waist circumference adjusted for body mass index ( 34021172)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		9 interacting genes: BCL2L11 CASP10 CDC42 CREB3L3 FBXO25 PAK2 SMURF1 TULP3 UBC	62 interacting genes: ACTN2 AKAP9 ANKRD1 ANKRD54 ARHGAP21 ARMCX2 ATP2A1 BACH2 BOC BRMS1L BTBD1 CCNB1 CHD2 CLIP4 DNTTIP2 DROSHA DST ESRRG GPATCH2L GSE1 HSF2BP KIF3A KLF10 KRTAP10-1 KRTAP10-5 KRTAP10-7 MAGEA6 MAP3K5 MBTD1 MGA MORF4L1 MYBPC2 MYH3 MYH7 MYO18B NCOR1 NFE2L1 NOSTRIN NRIP1 PAF1 PCGF6 PDE4DIP PHAX PSTPIP1 RCOR3 RIOK3 RNF10 ROPN1 RYR1 SLAIN2 SPTB SRP72 TNNT1 TNNT3 WNK1 ZFAT ZNF160 ZNF462 ZNF619 ZNF793 ZNF835 ZSCAN23
Entrez ID		8780	7289
HPRD ID		04659	05292
Ensembl ID		ENSG00000101782	ENSG00000078246
Uniprot IDs		B0YJ89 B4E1Q4 O14730	B7Z1E7 O75386
PDB IDs
Enriched GO Terms of Interacting Partners?
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