TNFSF14 and CLDN11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TNFSF14	CLDN11
Description		TNF superfamily member 14	claudin 11
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Membrane	Lipid Droplet Neurofilament Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Cell Junction Axon Basal Part Of Cell Tight Junction
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Apoptotic Process Immune Response Signal Transduction T Cell Costimulation T Cell Proliferation T Cell Activation T Cell Homeostasis Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Mechanical Stimulus Positive Regulation Of NIK/NF-kappaB Signaling	Cell Adhesion Spermatogenesis Axon Ensheathment Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly Tight Junction Assembly
Pathways		TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Tight junction interactions
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Blood protein levels in cardiovascular risk ( 28369058) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte count ( 29403010) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 24076602 21833088)	Blood glucose levels ( 31928498) Monocyte chemoattractant protein-1 (red blood cell fatty acid level interaction) ( 28820441) Prostate cancer ( 21743467)
Interacting Genes		25 interacting genes: ADAM33 ADIPOQ APP BMP10 CLDN11 CLDN19 CXCL9 JAGN1 LHFPL3 LTB LTBR MAL OLFM4 PLLP PTTG1IP S1PR4 SEC22A SEC23A SLC38A3 SYS1 TCF3 TMEM11 TNFRSF14 TNFRSF6B UPK2	12 interacting genes: AMIGO1 C16orf54 FNDC9 KLRC1 SHISA3 SMIM3 SPINT1 TMEM80 TNFSF14 TSPAN3 TSPAN4 ZP3
Entrez ID		8740	5010
HPRD ID		05157	03207
Ensembl ID		ENSG00000125735	ENSG00000013297
Uniprot IDs		O43557	O75508
PDB IDs		4EN0 4J6G 4KG8 4KGG 4KGQ 4RSU
Enriched GO Terms of Interacting Partners?
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