CBR3 and RAB35

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CBR3	RAB35
Description		carbonyl reductase 3	RAB35, member RAS oncogene family
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GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytosol	Cytosol Plasma Membrane Clathrin-coated Pit Endosome Membrane Clathrin-coated Endocytic Vesicle Membrane Cell Projection Membrane Melanosome Intercellular Bridge Clathrin-coated Endocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	3-keto Sterol Reductase Activity Carbonyl Reductase (NADPH) Activity Protein Binding Oxidoreductase Activity NADPH Binding	GTPase Activity Protein Binding GTP Binding Phosphatidylinositol-4,5-bisphosphate Binding GDP Binding
	Biological Process	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition	Mitotic Cytokinesis Protein Localization Protein Transport Endosomal Transport Antigen Processing And Presentation Neuron Projection Development Endocytic Recycling Rab Protein Signal Transduction Protein Localization To Endosome Plasma Membrane To Endosome Transport Cellular Response To Nerve Growth Factor Stimulus
Pathways		Phase I - Functionalization of compounds	TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Lumbar spine bone mineral density ( 22504420)	Heel bone mineral density ( 30598549)
Interacting Genes		15 interacting genes: ANK1 ARIH2 ATP5PO BICD2 CLU IL10RB ITSN1 KCNE1 KCNJ15 PCP4 RAB35 RCAN1 SDCBP SHOX2 UBC	10 interacting genes: APP CALCOCO2 CBR3 GNPAT IDH3B MPHOSPH9 PTPRS TBPL1 TRIM54 WDCP
Entrez ID		874	11021
HPRD ID		07222	05010
Ensembl ID		ENSG00000159231	ENSG00000111737
Uniprot IDs		O75828 V9HW40	Q15286
PDB IDs		2HRB	3TW8 6EKK 6IF2 6IF3
Enriched GO Terms of Interacting Partners?
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